A 45-year-old man has new hypertension, creatinine 148 micromol/L, microscopic haematuria, and subnephrotic proteinuria. Complement C3 is low,

Question

A 45-year-old man has new hypertension, creatinine 148 micromol/L, microscopic haematuria, and subnephrotic proteinuria. Complement C3 is low, hepatitis C antibody is positive, and rheumatoid factor is positive. He has palpable purpura on the legs. What is the most appropriate investigation?

Accepted Answer

Kidney biopsy with immunofluorescence

Answer

Repeat urine dipstick in 6 months

Answer

Genetic testing for Alport syndrome

Answer

Renal ultrasound alone

Answer

Urine eosinophils

Cryoglobulinaemic glomerulonephritis — RCPSC IM MCQ

A 45-year-old man has new hypertension, creatinine 148 micromol/L, microscopic haematuria, and subnephrotic proteinuria. Complement C3 is low, hepatitis C antibody is positive, and rheumatoid factor is positive. He has palpable purpura on the legs. What is the most appropriate investigation?