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Hyperkalemia — RCPSC IM MCQ

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HardNephrologyHyperkalemiaRCPSC IM

A patient with suspected immune TTP has platelets 12 ×10⁹/L, schistocytes, high LDH, confusion and normal coagulation studies. ADAMTS13 result will take 48 hours. What is the immediate treatment approach?

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Correct answer: D — Begin plasma exchange and corticosteroids while ADAMTS13 testing is pending

Immune TTP is a treatment emergency; plasma exchange and corticosteroids begin on clinical suspicion rather than waiting for ADAMTS13. Platelets can worsen thrombosis when there is no major bleeding, eculizumab is for complement-mediated TMA, and fluids or anticoagulation do not treat the mechanism.

Reference: Thrombosis Canada, Clinical Guides: https://thrombosiscanada.ca/hcp/practice/clinical_guides