skip to main content

Long-acting opioid overdose — RCPSC EM MCQ

Instant feedback + full explanation. One question, done properly.

ModerateToxicologyLong-acting opioid overdoseRCPSC EM

A 21-year-old ingests unknown tablets and is now awake after naloxone. RR is 14, SpO2 96%, but he required three naloxone boluses over two hours. Friends report possible long-acting opioid exposure. What is the most appropriate disposition?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — Admit for monitored observation with naloxone infusion considered

Recurrent respiratory depression after naloxone and possible long-acting opioid exposure require monitored observation and often infusion, with harm-reduction planning.

Reference: Poison centre toxicology guidance; Goldfrank-style ED toxicology principles