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COPD exacerbation with hypercapnic respiratory failure — RCPSC EM MCQ

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HardRespiratory emergenciesCOPD exacerbation with hypercapnic respiratory failureRCPSC EM

A 71-year-old man with severe COPD presents CTAS 2 with worsening dyspnoea and drowsiness. RR is 32, SpO2 is 86% on 2 L nasal oxygen, BP is 156/84, and ABG shows pH 7.24, PaCO2 78 mmHg, HCO3 31 mmol/L. Chest X-ray shows hyperinflation without consolidation. What is the most appropriate next step?

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Correct answer: DStart non-invasive ventilation with controlled oxygen and bronchodilator therapy

Acute hypercapnic respiratory failure from COPD exacerbation with acidaemia is an indication for NIV with controlled oxygen, alongside bronchodilators and treatment of triggers.

Reference: CAEP Clinical Practice Guidelines