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Tuberculosis infection — RACP Paediatrics MCQ

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HardInfectious diseases and immunisationTuberculosis infectionRACP Paediatrics

A 9-year-old recently arrived from a high-incidence country. His father has smear-positive pulmonary tuberculosis. The child is well, chest X-ray is normal and interferon-gamma release assay is positive. What is the most appropriate investigation?

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Correct answer: CSputum or gastric aspirate testing if symptoms develop; assess for latent TB treatment now

Positive immune testing after close exposure with a normal chest X-ray supports TB infection rather than active pulmonary disease. The key next step is specialist assessment for latent TB treatment and monitoring, with microbiology if symptoms or radiographic changes suggest disease. A normal chest X-ray does not remove the risk of progression in a close contact.

Reference: Australian TB guidelines; RACP Knowledge Guides