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Crohn disease — RACP Paediatrics MCQ

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HardGastroenterologyCrohn diseaseRACP Paediatrics

A 13-year-old has three months of weight loss, mouth ulcers, right iliac fossa pain and non-bloody diarrhoea. CRP and faecal calprotectin are elevated, and perianal skin tags are present. What is the most likely diagnosis?

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Correct answer: C — Crohn disease

Crohn disease is likely with systemic inflammation, raised calprotectin, perianal disease, mouth ulcers and weight loss. Irritable bowel syndrome should not cause raised inflammatory markers or perianal disease. Endoscopy with biopsies is needed to establish diagnosis and disease extent.

Reference: RACP Knowledge Guides; Australian IBD standards