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Dopamine agonist impulse-control disorder — DGM MCQ

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HardMovement disordersDopamine agonist impulse-control disorderDGM

An 82-year-old man with Parkinson's disease has new gambling behaviour and hypersexuality. His motor symptoms are controlled. Medicines include ropinirole, co-careldopa, ramipril, atorvastatin and macrogol. Which medication should be reviewed?

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Correct answer: E — Ropinirole

Dopamine agonists such as ropinirole are strongly associated with impulse-control disorders. Co-careldopa can contribute to hallucinations or dyskinesia, but impulse-control behaviour is particularly linked to dopamine agonists. Patients and families should be warned about this adverse effect before and during therapy.

Reference: NICE NG71; BNF