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Oxybutynin cognitive adverse effects — DGM MCQ

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ModeratePolypharmacyOxybutynin cognitive adverse effectsDGM

An 82-year-old man with chronic constipation and mild cognitive impairment has urgency incontinence. He takes oxybutynin, senna, aspirin, simvastatin and colecalciferol. His son reports increasing forgetfulness since the continence medicine was increased. Which medication should be reviewed?

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Correct answer: C — Oxybutynin

Oxybutynin has significant anticholinergic effects and can worsen cognition and constipation. Senna may cause cramps but does not explain cognitive decline. In frail older adults, bladder antimuscarinics should be reviewed when cognitive or bowel symptoms worsen.

Reference: BNF; NICE NG123