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Alzheimer's disease — DGM MCQ

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EasyDementiaAlzheimer's diseaseDGM

A 79-year-old woman has 18 months of gradually progressive short-term memory loss. She repeats questions, misplaces items and needs help managing bills. Neurological examination is normal and there are no hallucinations, stroke episodes or prominent gait symptoms. What is the most likely diagnosis?

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Correct answer: C — Alzheimer's disease

Gradual episodic memory decline with progressive functional impairment is most typical of Alzheimer's disease. Delirium would be acute and fluctuating, and dementia with Lewy bodies usually has early visual hallucinations, parkinsonism or cognitive fluctuation. Functional decline is the key distinction between mild cognitive symptoms and dementia.

Reference: NICE NG97