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Amlodipine adverse effects — DGM MCQ

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ModeratePolypharmacyAmlodipine adverse effectsDGM

An 84-year-old woman has new ankle swelling and facial flushing after treatment for hypertension. She has normal urinalysis and no breathlessness. Her medicines are amlodipine, ramipril, atorvastatin, metformin and colecalciferol. Which medication should be reviewed?

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Correct answer: A — Amlodipine

Peripheral oedema and flushing are common dose-related adverse effects of dihydropyridine calcium-channel blockers such as amlodipine. Heart failure should be considered if breathlessness or raised JVP are present, but the clean scenario points to medication effect. Adverse drug reactions should be considered before adding another medicine to treat a side effect.

Reference: BNF Prescribing in elderly