skip to main content

Bisphosphonate oesophageal irritation — DGM MCQ

Instant feedback + full explanation. One question, done properly.

ModerateFallsBisphosphonate oesophageal irritationDGM

An 87-year-old woman with osteoporosis develops epigastric pain and dysphagia after starting weekly alendronate. She has eGFR 58 mL/min/1.73 m2 and takes calcium and vitamin D. She admits lying down soon after taking the tablet. What is the most appropriate management?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Stop alendronate temporarily and review administration technique and alternatives

Oesophageal symptoms after oral bisphosphonate warrant stopping and reviewing technique, contraindications and alternative bone protection. Continuing unchanged risks oesophageal injury. Oral bisphosphonates require specific administration, including taking with water and remaining upright.

Reference: BNF; NICE TA464