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Live vaccines and immunosuppression — DCH MCQ

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HardImmunisationLive vaccines and immunosuppressionDCH

A 5-year-old boy receiving chemotherapy for acute lymphoblastic leukaemia is brought for catch-up vaccinations. He is clinically stable but remains immunosuppressed. What is the most important red flag?

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Correct answer: B — Giving live vaccines while immunosuppressed

Live vaccines are generally contraindicated during significant immunosuppression and should be planned with specialist advice. Combination vaccines and accurate documentation are routine parts of safe immunisation practice. The pearl is that household vaccination may still be important to protect immunosuppressed children indirectly.

Reference: UKHSA Green Book Immunisation of immunosuppressed persons