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Early-onset neonatal infection — DCH MCQ

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HardNeonatologyEarly-onset neonatal infectionDCH

A 2-day-old baby is hypothermic, feeding poorly and has grunting respirations. Maternal history includes prolonged rupture of membranes and intrapartum fever. What is the most likely diagnosis?

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Correct answer: DEarly-onset neonatal infection

Poor feeding, hypothermia and respiratory signs in a neonate are concerning for early-onset infection, especially with maternal risk factors. Absence of fever is not reassuring in newborn sepsis. The teaching point is that neonatal infection may present with low temperature, lethargy or feeding difficulty rather than fever.

Reference: NICE NG195