Developmental regression — DCH MCQ

Correct answer: B — Loss of previously acquired skills

The correct answer is B: loss of previously acquired skills. This child has developmental regression affecting language and play, rather than simply delayed acquisition of new skills. Regression is a major developmental red flag requiring urgent paediatric assessment and investigation. The associated reduction in eye contact and repetitive movements raises the possibility of autism, but regression can also occur with neurological, genetic or metabolic disorders and should not automatically be attributed to autism. Preference for repetition, tantrums around transitions and food selectivity may occur in typically developing toddlers as well as in neurodevelopmental conditions. Shyness with unfamiliar adults is also common at this age. None is as concerning as a definite loss of established abilities.

Reference: NHS England Genomics Education Programme. Presentation: Patient with developmental delay, reviewed 6 February 2026. https://www.genomicseducation.hee.nhs.uk/genotes/in-the-clinic/patient-with-developmental-delay/