Anaphylaxis — MCCQE Part 1 MCQ
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Correct answer: B — Give intramuscular epinephrine into the mid-anterolateral thigh
Multisystem allergic reaction with hypotension is anaphylaxis; intramuscular epinephrine is first-line and should not be delayed. Antihistamines and steroids are adjuncts and do not treat shock or airway oedema promptly. Salbutamol helps bronchospasm but is not definitive. Tryptase can support later evaluation but treatment is clinical.
Reference: Canadian Society of Allergy and Clinical Immunology anaphylaxis guidance