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Paediatric diabetic ketoacidosis — MCCQE Part 1 MCQ

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HardAbdominal PainPaediatric diabetic ketoacidosisMCCQE Part 1

A 10-year-old child presents with polyuria, weight loss, vomiting, and abdominal pain. He is dehydrated and breathing deeply. Glucose is 29 mmol/L, pH is 7.18, bicarbonate is 9 mmol/L, and ketones are positive. What is the most appropriate next step in management?

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Correct answer: BBegin paediatric DKA protocol with isotonic fluids and intravenous insulin

Paediatric DKA requires a protocolised approach with careful isotonic fluids, insulin infusion, electrolyte monitoring, and vigilance for cerebral injury. Rapid overcorrection and inappropriate fluid strategies increase harm. Routine bicarbonate is generally avoided. Metformin and basal insulin alone are not acute DKA treatment.

Reference: CPS; Diabetes Canada paediatric diabetes guidance