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Pregnancy of unknown location — DRCOG MCQ

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HardEarly PregnancyPregnancy of unknown locationDRCOG

A 30-year-old woman has a positive pregnancy test, mild pelvic pain and no intrauterine pregnancy on transvaginal scan. Her initial hCG is 720 IU/L and 48 hours later it is 900 IU/L. She is stable with no free fluid. What is the most appropriate investigation?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: ASerial serum hCG with repeat transvaginal ultrasound follow-up

This is a pregnancy of unknown location with a suboptimal hCG rise, so serial hCG and repeat ultrasound through EPAU are required. Progesterone cannot definitively locate the pregnancy. The pearl is that PUL requires follow-up until the pregnancy location and outcome are clear.

Reference: NICE NG126