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Gestational trophoblastic disease — DRCOG MCQ

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HardEarly PregnancyGestational trophoblastic diseaseDRCOG

A 19-year-old woman has vaginal bleeding at 11 weeks. Ultrasound shows a heterogeneous intrauterine mass with no viable fetus, and serum hCG is markedly higher than expected for gestation. She has severe nausea. What is the most likely diagnosis?

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Correct answer: AHydatidiform mole

Markedly raised hCG, severe nausea and a heterogeneous intrauterine mass are typical of molar pregnancy. Threatened miscarriage would have a viable intrauterine pregnancy and does not explain very high hCG with this scan appearance. The pearl is that suspected gestational trophoblastic disease needs specialist follow-up after evacuation.

Reference: RCOG Green-top Guideline No. 38; NICE NG126