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Aneuploidy screening — DRCOG MCQ

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HardAntenatal CareAneuploidy screeningDRCOG

A woman presents at 16+2 weeks after missing first-trimester aneuploidy screening. She wants screening and has not had a previous higher-chance result. What should be offered?

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Correct answer: C — The second-trimester quadruple blood test

The best answer is “The second-trimester quadruple blood test”. The NHS programme offers the quadruple test from 14+2 to 20+0 weeks when the combined-test window has passed. It is a screening test; chorionic villus sampling and amniocentesis are diagnostic tests, while NHS NIPT is generally contingent on a higher-chance initial result.

Reference: NHS Fetal Anomaly Screening Programme handbook: https://www.gov.uk/government/publications/fetal-anomaly-screening-programme-handbook/screening-for-downs-syndrome-edwards-syndrome-and-pataus-syndrome--3