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Epilepsy in pregnancy — DRCOG MCQ

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HardAntenatal CareEpilepsy in pregnancyDRCOG

A 30-year-old woman attends pre-conception counselling. She takes sodium valproate for epilepsy and has been seizure-free for 2 years. She wants to start trying for pregnancy next month. What is the most appropriate management?

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Correct answer: BRefer for specialist review before conception

Valproate is highly teratogenic and women planning pregnancy need specialist review to consider safer treatment and optimise folic acid before conception. Abrupt discontinuation may cause seizures and should not be advised in primary care. The pearl is that medication optimisation should occur before conception, not at the booking visit.

Reference: NICE NG217; MHRA valproate pregnancy prevention programme