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Tranexamic acid in major haemorrhage — DipIMC MCQ

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ModeratePharmacologyTranexamic acid in major haemorrhageDipIMC

A 25-year-old motorcyclist has suspected pelvic and abdominal haemorrhage after a collision 45 minutes ago. He is pale, pulse 138/min and systolic blood pressure 82 mmHg; IV access is present. What is the most appropriate drug/dose?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Tranexamic acid 1 g IV as soon as possible

TXA should be given early in suspected major traumatic haemorrhage, ideally within 3 hours. Waiting for CT defeats the time-dependent benefit in a patient with clinical shock. Antiplatelet or anticoagulant drugs would worsen haemorrhage risk.

Reference: JRCALC Guidelines; NICE NG39 Major trauma