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Opioid overdose — MCCQE Part 1 MCQ

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EasyPoisoning/OverdoseOpioid overdoseMCCQE Part 1

A 32-year-old man is found unresponsive in a public washroom with slow respirations and pinpoint pupils. Oxygen saturation is 78% and bystanders report possible fentanyl use. What is the most appropriate next step in management?

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Correct answer: B — Support ventilation and administer naloxone

Respiratory depression with miosis after suspected fentanyl exposure is opioid overdose; ventilation support and naloxone are immediate priorities. Toxicology confirmation should not delay treatment. Methadone may be used for opioid use disorder later, not acute respiratory arrest.

Reference: Canadian opioid overdose guidance; Health Canada naloxone resources