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Polycystic ovary syndrome — MCCQE Part 1 MCQ

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ModerateInfertilityPolycystic ovary syndromeMCCQE Part 1

A 28-year-old woman presents with 14 months of infertility and irregular menses every 45–70 days. She has acne, BMI 33 kg/m² and increased terminal hair on the chin. TSH and prolactin are normal. What is the most likely diagnosis?

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Correct answer: A — Polycystic ovary syndrome

Oligo-ovulation with clinical hyperandrogenism after excluding thyroid and prolactin disorders is consistent with PCOS. Premature ovarian insufficiency usually presents with elevated FSH and hypo-oestrogenic symptoms. Endometriosis may cause infertility but does not explain hyperandrogenism and oligomenorrhoea.

Reference: International PCOS Guideline; SOGC infertility resources