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Asthma diagnosis — ABFM Board MCQ

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ModerateRespiratoryAsthma diagnosisABFM Board

A 41-year-old man has episodic wheezing and cough triggered by cold air. Spirometry shows FEV1/FVC below the lower limit of normal with 15% and 300 mL improvement in FEV1 after albuterol. Which of the following is the most likely diagnosis?

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Correct answer: E — Asthma

Variable airflow obstruction with significant bronchodilator reversibility supports asthma. COPD is less likely in a younger nonsmoker with reversible symptoms and cold-air triggers.

Reference: GINA Strategy Report, 2024