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Uncomplicated cystitis — ABFM Board MCQ

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ModerateUrology/RenalUncomplicated cystitisABFM Board

A 29-year-old woman has dysuria and urinary frequency for 1 day. She is not pregnant, has no fever, flank pain, vaginal discharge, or recent urinary tract instrumentation. Urine dipstick is positive for leukocyte esterase and nitrites. Which of the following is the most appropriate initial treatment?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Nitrofurantoin for 5 days

Uncomplicated cystitis in a nonpregnant woman can be treated empirically with nitrofurantoin for 5 days. Fluoroquinolones and imaging are unnecessary for typical lower urinary tract infection without systemic features.

Reference: IDSA Uncomplicated Cystitis Guideline