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COPD exacerbation — ABFM Board MCQ

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ModerateRespiratoryCOPD exacerbationABFM Board

A 70-year-old man with COPD reports increased dyspnea and sputum volume for 2 days. He is afebrile, oxygen saturation is 93% on room air, and chest examination has diffuse wheeze without focal crackles. Which of the following is the most appropriate initial treatment?

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Correct answer: B — Oral prednisone and short-acting bronchodilators

An outpatient COPD exacerbation is treated with short-acting bronchodilators and a short course of systemic corticosteroids. Antibiotics are considered when sputum purulence or more severe features are present.

Reference: GOLD COPD Report, 2025