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Opioid use disorder — ABFM Board MCQ

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ModerateMental healthOpioid use disorderABFM Board

A 35-year-old man requests medication for opioid use disorder. He uses nonprescribed oxycodone daily, has mild withdrawal symptoms, and wants office-based treatment. He has no benzodiazepine use and no severe hepatic disease. Which of the following is the most appropriate initial treatment?

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Correct answer: D — Buprenorphine-naloxone induction with counseling and follow-up

Buprenorphine-naloxone is effective office-based treatment for opioid use disorder and can be initiated when the patient has objective withdrawal. Naltrexone requires opioid-free status to avoid precipitated withdrawal.

Reference: SAMHSA Buprenorphine Quick Start Guide