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Systemic lupus erythematosus — ABFM Board MCQ

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HardDermatologySystemic lupus erythematosusABFM Board

A 29-year-old woman has malar rash sparing the nasolabial folds, photosensitivity, arthralgias, oral ulcers, and proteinuria. ANA is positive and anti-dsDNA is elevated. Which of the following is the most likely diagnosis?

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Correct answer: C — Systemic lupus erythematosus

Photosensitive malar rash, oral ulcers, inflammatory symptoms, proteinuria, positive ANA, and anti-dsDNA antibodies support systemic lupus erythematosus with possible renal involvement.

Reference: ACR/EULAR SLE Classification Criteria