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Major depressive disorder — ABFM Board MCQ

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EasyMental healthMajor depressive disorderABFM Board

A 32-year-old man reports low mood, anhedonia, poor sleep, and guilt for 6 weeks. He denies suicidal ideation, mania, psychosis, and substance misuse. PHQ-9 score is 16. Which of the following is the most appropriate initial treatment?

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Correct answer: A — Psychotherapy, an SSRI, or both

Moderate major depressive disorder can be treated with evidence-based psychotherapy, an antidepressant such as an SSRI, or a combination based on patient preference and clinical context. Bipolar disorder and suicide risk should be assessed.

Reference: APA Depression Guideline; USPSTF Depression Screening Recommendation