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Pheochromocytoma — ABFM Board MCQ

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HardEndocrine/MetabolicPheochromocytomaABFM Board

A 46-year-old woman has episodic headaches, sweating, and palpitations. Blood pressure in clinic is 184/106 mm Hg, potassium is normal, and plasma free metanephrines are markedly elevated. CT shows a 3-cm adrenal mass. Which of the following is the most likely diagnosis?

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Correct answer: B — Pheochromocytoma

Paroxysmal headaches, sweating, palpitations, severe hypertension, elevated metanephrines, and an adrenal mass strongly indicate pheochromocytoma. Preoperative alpha blockade is needed after diagnosis.

Reference: Endocrine Society Pheochromocytoma Guideline