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Severe hypercholesterolemia — ABFM Board MCQ

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ModerateCardiovascularSevere hypercholesterolemiaABFM Board

A 47-year-old man has LDL cholesterol 194 mg/dL on a fasting lipid panel. He has no diabetes, no ASCVD, and normal liver enzymes. Which of the following would you advise this patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — High-intensity statin therapy

An LDL cholesterol level of 190 mg/dL or higher is an indication for high-intensity statin therapy after evaluation for secondary causes, regardless of calculated 10-year ASCVD risk.

Reference: ACC/AHA Cholesterol Guideline