Intrahepatic cholestasis of pregnancy — USMLE Step 3 MCQ
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Correct answer: B — Plan cesarean hysterectomy at 34–35 weeks with placenta left in situ
The best answer is “Plan cesarean hysterectomy at 34–35 weeks with placenta left in situ”. Suspected placenta accreta spectrum should be managed by a multidisciplinary experienced center. Planned cesarean hysterectomy before labor or bleeding, generally at 34 0/7–35 6/7 weeks, with the placenta left undisturbed reduces catastrophic hemorrhage; forced placental removal is dangerous.
Reference: ACOG Obstetric Care Consensus: Placenta Accreta Spectrum: https://www.acog.org/clinical/clinical-guidance/obstetric-care-consensus/articles/2018/12/placenta-accreta-spectrum