A patient develops HAP with septic shock after 9 days in the ICU. He received intravenous antibiotics 2 weeks ago; the unit antibiogram shows more

Question

A patient develops HAP with septic shock after 9 days in the ICU. He received intravenous antibiotics 2 weeks ago; the unit antibiogram shows more than 10% resistance among gram-negative isolates, and respiratory MRSA prevalence is 18%. Which empiric regimen is appropriate pending cultures?

Accepted Answer

Use MRSA coverage plus two antipseudomonal agents from different classes

Answer

Use vancomycin plus two agents from the same antipseudomonal class

Answer

Use vancomycin plus one antipseudomonal beta-lactam pending respiratory cultures

Answer

Use linezolid plus one antipseudomonal beta-lactam pending respiratory cultures

Answer

Use two antipseudomonal agents without empiric MRSA coverage pending cultures

Postoperative hospital-acquired pneumonia — USMLE Step 3 MCQ

A patient develops HAP with septic shock after 9 days in the ICU. He received intravenous antibiotics 2 weeks ago; the unit antibiogram shows more than 10% resistance among gram-negative isolates, and respiratory MRSA prevalence is 18%. Which empiric regimen is appropriate pending cultures?