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Postoperative proximal DVT — USMLE Step 3 MCQ

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HardSurgeryPostoperative proximal DVTUSMLE Step 3

A 49-year-old outpatient has mild calf pain after a 7-hour flight. Ultrasound shows an isolated posterior tibial-vein thrombosis 3 cm long, more than 5 cm below the popliteal vein. He has no cancer, prior VTE, immobility, severe symptoms, or bleeding risk and can return reliably. Which strategy is most appropriate?

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Correct answer: BUse serial compression ultrasonography for 2 weeks and anticoagulate if extension occurs

The best answer is “Use serial compression ultrasonography for 2 weeks and anticoagulate if extension occurs”. This is low-risk isolated distal DVT without extension-risk features. CHEST guidance supports serial imaging for 2 weeks rather than immediate anticoagulation; therapeutic anticoagulation is started if thrombus extends or if high-risk features make surveillance inappropriate.

Reference: CHEST Guideline: Antithrombotic Therapy for VTE Disease: https://journal.chestnet.org/article/S0012-3692(21)01506-3/fulltext