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HPV catch-up vaccination — USMLE Step 3 MCQ

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EasyAmbulatory Medicine / Primary CareHPV catch-up vaccinationUSMLE Step 3

A 19-year-old woman comes for a college physical. She has no chronic conditions and takes no medications. She completed routine childhood vaccines but has not received HPV vaccination. She is sexually active with one male partner. Which of the following is the most appropriate at this time?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Start the HPV vaccine series

Catch-up HPV vaccination is recommended through age 26 for those not adequately vaccinated. Cervical cancer screening begins at age 21 regardless of sexual activity.

Reference: CDC Adult Immunization Schedule 2025; USPSTF Cervical Cancer Screening Recommendation