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Uncomplicated chlamydial urethritis — USMLE Step 3 MCQ

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EasyAmbulatory Medicine / Primary CareUncomplicated chlamydial urethritisUSMLE Step 3

A 27-year-old man has dysuria and urethral discharge. Nucleic acid amplification testing is positive for Chlamydia trachomatis and negative for Neisseria gonorrhoeae. He has no drug allergies and is not taking medications. Which of the following is the most appropriate next step in management?

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Correct answer: D — Doxycycline for 7 days and partner notification

Doxycycline for 7 days is preferred for uncomplicated chlamydial infection in nonpregnant adults. Partners require evaluation and treatment to prevent reinfection and onward transmission.

Reference: CDC Sexually Transmitted Infections Treatment Guidelines 2021