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Hyperosmolar hyperglycaemic state — SCE Endocrinology MCQ

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HardDiabetesHyperosmolar hyperglycaemic stateSCE Endocrinology

A 79-year-old woman with type 2 diabetes is admitted after 5 days of thirst, confusion and reduced intake. Glucose is 43 mmol/L, osmolality 342 mOsm/kg, ketones 0.8 mmol/L, pH 7.36 and sodium is 151 mmol/L. Chest radiograph shows right lower-zone pneumonia. What is the most likely diagnosis?

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Correct answer: EHyperosmolar hyperglycaemic state

Marked hyperosmolality, severe hyperglycaemia and minimal ketosis are typical of HHS. DKA would have significant ketonaemia and acidosis. The pearl is that HHS management prioritises gradual osmolality correction and treating the precipitant.

Reference: JBDS 06 HHS guideline