skip to main content

Familial hypocalciuric hypercalcaemia — SCE Endocrinology MCQ

Instant feedback + full explanation. One question, done properly.

ModerateCalcium/BoneFamilial hypocalciuric hypercalcaemiaSCE Endocrinology

A 44-year-old man has repeated calcium 2.76 mmol/L with PTH 7.4 pmol/L. He is asymptomatic and his mother has lifelong mild hypercalcaemia. Urine calcium:creatinine clearance ratio is 0.006. What is the most likely diagnosis?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Familial hypocalciuric hypercalcaemia

Low urinary calcium excretion with lifelong familial mild hypercalcaemia suggests familial hypocalciuric hypercalcaemia. Primary hyperparathyroidism typically has higher urinary calcium excretion. The pearl is that parathyroidectomy does not correct FHH and should be avoided.

Reference: NICE NG132, Endocrine Society calcium disorders guidance