Central diabetes insipidus — SCE Endocrinology MCQ
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Correct answer: E — Central diabetes insipidus
Hypernatraemia with dilute urine indicates water diuresis, and a strong response to desmopressin confirms central arginine vasopressin deficiency. Nephrogenic diabetes insipidus would show little response to desmopressin. The pearl is that postoperative pituitary water balance can change rapidly and needs close sodium monitoring.
Reference: Society for Endocrinology guidance on arginine vasopressin deficiency