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Hepatitis C screening — ABIM Board MCQ

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HardGeneral Internal MedicineHepatitis C screeningABIM Board

A 37-year-old man previously had a negative hepatitis C antibody test and now injects drugs intermittently. What testing approach is most appropriate?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: ARepeat hepatitis C testing periodically while exposure risk continues

People with ongoing hepatitis C exposure risk should receive periodic repeat testing even after a prior negative screen. Waiting for symptoms or aminotransferase elevation misses opportunities for diagnosis and treatment.

Reference: USPSTF: Hepatitis C Virus Infection Screening: https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/hepatitis-c-screening