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Hereditary angioedema — ABIM Board MCQ

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HardRheumatology/Allergy/ImmunologyHereditary angioedemaABIM Board

A 55-year-old with obesity, type 2 diabetes, and persistently elevated aminotransferases has steatosis on ultrasound. There is no substantial alcohol use or viral hepatitis. What is the appropriate next step to assess liver risk?

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Correct answer: D — Calculate a noninvasive fibrosis risk score such as FIB-4

In patients with suspected metabolic steatotic liver disease, noninvasive fibrosis risk assessment is used first to identify those who need specialty referral or further testing. Aminotransferase values and steatosis imaging alone do not reliably stage fibrosis.

Reference: AASLD Practice Guidance: NAFLD Clinical Assessment and Management: https://www.aasld.org/sites/default/files/2022-06/NAFLD%20Guidance%202018.pdf