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Serotonin syndrome — ABEM Board MCQ

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ModerateToxicologySerotonin syndromeABEM Board

A 26-year-old woman arrives as ESI 2 after taking sertraline and linezolid. Temperature is 39.4 C, BP 168/92, HR 142. She is agitated with inducible ankle clonus, hyperreflexia, and diarrhea. Which of the following is the most likely diagnosis?

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Correct answer: DSerotonin syndrome

Serotonergic exposure with clonus, hyperreflexia, agitation, hyperthermia, and diarrhea supports serotonin syndrome.

Reference: Goldfrank Toxicologic Emergencies; Hunter Serotonin Toxicity Criteria