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Febrile neutropenia with sepsis — RCPSC EM MCQ

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HardInfectious disease emergenciesFebrile neutropenia with sepsisRCPSC EM

An adult remains hypotensive after two correctly timed IM epinephrine doses and adequate crystalloid. A resuscitation physician, infusion pump and continuous monitoring are available. What is the next vasopressor strategy?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: CStart a low-dose titrated IV epinephrine infusion with continuous resuscitation monitoring

Explanation lettering: C = shown as A · A = shown as B · B = shown as C · E = shown as D · D = shown as E

B is correct for refractory anaphylactic shock in a monitored expert setting. C uses cardiac-arrest dosing and risks fatal arrhythmia. D has poor absorption in shock. E substitutes a non-resuscitative adjunct. A is mainly an adjunct when beta-blockade contributes to refractory shock.

Reference: Canadian Immunization Guide, Anaphylaxis and other acute reactions: https://emergencycarebc.ca/clinical_resource/clinical-summary/anaphylaxis-diagnosis-treatment/