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Wernicke encephalopathy — RCPSC EM MCQ

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ModerateNeurological emergenciesWernicke encephalopathyRCPSC EM

A 49-year-old with alcohol use disorder is confused and ataxic with horizontal nystagmus. Glucose is 3.9 mmol/L, magnesium is low, and there are no focal deficits. What is the most appropriate next step?

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Correct answer: CGive intravenous thiamine before glucose-containing fluids when feasible, plus magnesium repletion

The triad of confusion, ataxia and ophthalmoplegia/nystagmus suggests Wernicke encephalopathy; thiamine should be given promptly.

Reference: Canadian addiction medicine and emergency neurology practice