A patient on chemotherapy has temperature 39.0°C, ANC 0.1×10⁹/L, BP 88/50 mmHg and a tunneled line without exit-site inflammation. What antimicrobial

Question

A patient on chemotherapy has temperature 39.0°C, ANC 0.1×10⁹/L, BP 88/50 mmHg and a tunneled line without exit-site inflammation. What antimicrobial plan is correct?

Accepted Answer

Obtain cultures and start IV antipseudomonal therapy, adding vancomycin only for a defined indication

Answer

Give oral ciprofloxacin plus amoxicillin-clavulanate because all febrile neutropenia begins with outpatient therapy

Answer

Administer G-CSF first and begin antibiotics only if hypotension persists after neutrophil stimulation

Answer

Remove the tunneled line after peripheral cultures, then start antipseudomonal antibiotics

Answer

Give vancomycin alone because a central line makes Gram-positive infection the presumed cause

Febrile neutropenia — RCPSC EM MCQ

A patient on chemotherapy has temperature 39.0°C, ANC 0.1×10⁹/L, BP 88/50 mmHg and a tunneled line without exit-site inflammation. What antimicrobial plan is correct?