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Severe agitation with hyperthermia after stimulant use — RCPSC EM MCQ

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HardPsychiatric emergenciesSevere agitation with hyperthermia after stimulant useRCPSC EM

CTAS 1: A 25-year-old is brought by police after methamphetamine use. Vitals are T 40.2°C, HR 158, BP 182/96, RR 30. He is combative, diaphoretic and delirious. CK is pending; ECG shows sinus tachycardia. Staff cannot safely obtain IV access. What is the most appropriate initial management?

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Correct answer: BRapid benzodiazepine sedation with active cooling and monitoring

Excited delirium or severe sympathomimetic toxicity is life-threatening. Benzodiazepine sedation, cooling, fluids and complication screening reduce hyperthermia and rhabdomyolysis risk.

Reference: CAEP agitation resources; Canadian toxicology practice