Serotonin syndrome — RCPSC EM MCQ
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Correct answer: A — Titrate IV antihypertensive therapy to keep systolic pressure below 160 mmHg
The best answer is “Titrate IV antihypertensive therapy to keep systolic pressure below 160 mmHg”. Before definitive aneurysm treatment, control severe hypertension while preserving cerebral perfusion. Canadian emergency guidance uses a systolic target below 160 mmHg, with alert patients often managed nearer 140 mmHg and transfer to neurosurgical or neurointerventional care. Extreme lowering risks cerebral ischaemia, while no treatment, oral-only therapy or diuresis do not control rebleeding risk safely.
Reference: Emergency Care BC: Subarachnoid Hemorrhage—Treatment: https://emergencycarebc.ca/clinical_resource/clinical-summary/subarachnoid-hemorrhage-treatment/