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Febrile neutropenia — RCPSC EM MCQ

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ModerateInfectious disease emergenciesFebrile neutropeniaRCPSC EM

A 62-year-old man receiving chemotherapy presents with fever 38.7°C and chills. Absolute neutrophil count is 0.2 x 10^9/L, blood pressure is 98/56 mmHg, lactate is 2.9 mmol/L, and no source is clear. What is the most appropriate investigation?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Blood cultures from peripheral and central sites if this does not delay antibiotics

In febrile neutropenia, blood cultures from peripheral and central lines are appropriate when promptly obtainable, but antipseudomonal antibiotics must not be delayed.

Reference: Cancer Care Ontario febrile neutropenia guidance; Surviving Sepsis Campaign