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Salicylate poisoning — RCPSC EM MCQ

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HardToxicologySalicylate poisoningRCPSC EM

A 38-year-old woman presents with tinnitus, vomiting, tachypnoea, fever, and confusion after taking many aspirin tablets. ABG shows pH 7.48 with PaCO2 21 mmHg; chemistry shows bicarbonate 14 mmol/L and salicylate level is high. What is the most likely diagnosis?

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Correct answer: BSalicylate poisoning

Tinnitus, vomiting, tachypnoea, fever, and a mixed respiratory alkalosis with metabolic acidosis are typical of salicylate toxicity.

Reference: Ontario Poison Centre guidance; toxicology practice