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Depression — MRCGP AKT MCQ

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EasyExercise PrescriptionDepressionMRCGP AKT

A 45-year-old man with mild depression is inactive and asks whether exercise is worthwhile alongside psychological therapy. He has no physical contraindications. What is the physiological explanation?

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Correct answer: B — Regular physical activity can improve mood through behavioural, neurobiological and social mechanisms

Physical activity can reduce depressive symptoms and improve sleep, self-efficacy and social engagement. Neurobiological mechanisms include effects on monoamines, neurotrophic factors and inflammation. Exercise should be offered as part of a broader person-centred plan, not as a punitive prescription.

Reference: NICE depression guideline; FSEM